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Twist Bioscience

Mechanical Engineer - Automation Systems (Contract)

USA - Portland, ORcontractmidAdded today

About this role

Twist Bioscience seeks a contract mechanical engineer to design, build, and deploy custom automation systems for DNA synthesis manufacturing. This hands-on role spans CAD design through lab-floor assembly and testing, requiring expertise in SolidWorks, electromechanical integration, and fluidics systems over a 2–3 month engagement in Wilsonville, Oregon.

What you'll do

  • Design automated systems and custom mechanical components using SolidWorks to meet hardware requirements
  • Specify and procure mechanical, electromechanical, and fluidics components for complete automation platforms
  • Collaborate with cross-functional teams (systems engineers, electrical engineers, scientists) to refine requirements and optimize designs
  • Assemble, test, debug, and verify prototype systems on-site alongside technicians and engineering staff
  • Perform mechanical analyses including tolerance stack-up and design verification
  • Create and maintain comprehensive engineering documentation (3D models, drawings, BOMs, revision control)

What they're looking for

  • SolidWorks (part, assembly, and drawing design)
  • Custom automation and mechatronic systems design
  • Electromechanical component specification and integration (motors, actuators, sensors)
  • Fluidics systems design (pumps, valves, regulators, manifolds)
  • Tolerance analysis and mechanical design principles
  • Engineering documentation and BOM creation
  • Design for assembly and manufacturability
  • PLM systems (Dassault Systèmes 3DEXPERIENCE preferred)
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Twist Bioscience

Twist Bioscience builds DNA synthesis instruments and operates in a high-stakes manufacturing environment where precision and reliability are critical. The company is hiring Equipment Engineers to maintain, validate, and troubleshoot their specialized instruments while ensuring stringent quality standards.

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Likely interview questions

  • Walk us through a recent automation or mechatronic system you designed from concept to deployment—what were the key challenges?
  • Describe your experience integrating electromechanical components like motors and actuators into a larger system.